Geon Epilepsy and mTOR Topics


Over-production of Tau proteins has been demonstrated to cause hyperexcitability (see The Role of Microtubules in Epilepsy). The activation of mTOR increases Tau production (Caccamo et al., 2013; Tang et al., 2013; Tang et al., 2015). Therefore, hyperactive mTOR may promote epilepsy by enhancing excitability. This novel mechanism is supported by the following observations.


Author: Frank Lee
First published: December 9, 2015
Last updated: December 25, 2015